Evaluation of IGF-2 and IGF-2 receptor ligand (L1) in a rat model of AS on neurobehavioral phenotype.

Primary Investigator: Jill Silverman

The goals of this project are to evaluate the effects of IGF2 and IGF2RL in AS Rat model in domains of: ultrasonic communication, motor function, learning and memory, and gait as well as structural rescue by MRI (e.g. white matter loss).